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This medication is a fatty acid derivative mainly used as an antiepileptic drug, as well as for the treatment of bipolar disorder and prevention of migraines. How is the effect of the medication achieved? The medication inhibits the gamma-aminobutyric acid-transferase, increases the content of gamma-aminobutyric acid in the central nervous system, which causes a decrease in the threshold of excitability and the level of convulsive readiness of the motor zones of the brain. When ingested, it dissociates to valproate ion, which is absorbed into the blood plasma. Food decreases the absorption rate. The max concentration in plasma is observed 1-4 hours after the dosage intake.

It is metabolized in the liver: Metabolites and conjugates are excreted by the kidneys. A small amount of valproic acid is excreted in milk. Can you buy Generic Depakote instead of the branded drug? There is not a single reason against the purchase of the cheaper generic version of the mediation instead of the overpriced branded medicine that is more expensive only because of the known name. The formula of the medication is known since the nineteenth century and obviously is no longer protected by the copyright. It allows numerous pharmaceutical companies to use it without infringing any laws. The generics use is even promoted as it allows people from different income groups to get equally effective treatment.

But to be sure that you get the right medication especially if you purchase the pills online, make sure to check the name of the active substance which should be valproic acid and its amount per pill to get the right treatment. When is Depakote or its generic used? Depakote and all drugs with the same composition are appointed for the treatment of various forms of generalized seizures: Although you can buy Generic Depakote from this webpage without a valid prescription, we still encourage you if you have any seizures or suffer from migraines to go to a doctor first to get properly tested before you start taking any pills as these symptoms can signalize that you need more complex and thought-through therapy.

The drug must not be used by people, who are hypersensitive to it, i. The medication must not be also used by people with pancreas or liver dysfunction and in the presence of hemorrhagic diathesis. If you buy Divalproex while you have aplasia of the bone marrow, already use other anti-seizure medicines or plan to use this drug for therapy of children, make sure to consult a doctor as these factors are considered of high risk. What adverse effects can Divalproex use cause? When you get the medication, before you start taking it, you should be prepared that you may start suffering from certain side effects such as nausea, vomiting, diarrhea, pain in the abdomen, loss of appetite or increase of appetite, liver dysfunction, tremor, sleepiness, confusion, swelling, bleeding, and others.

If you have any allergic reactions or other reactions are severe — stop using Divalproex and talk to your healthcare provider. Interaction of Divalproex with other medicines When you buy Generic Divalproex, make sure to talk to your doctor about the possibility of using this medication with other ones that you use. The effect of the drug is enhanced in the use of other anti-seizure meds, sedatives, antidepressants, antipsychotics, and sleeping pills. Therefore, sometimes it is necessary to reduce the doses of these drugs. The use of medicines that negatively influence the liver function or alcohol along with Divalproex can cause more severe liver adverse reactions.

Anticoagulants, aspirin, and Divalproex mutually enhance the inhibitory effect on platelet aggregation, which requires strict control over the coagulating system of blood with the simultaneous use of these drugs. If you are experiencing stomach pain that extent to your back, vomiting and nausea, dark urination, appetite loss, swollen face or yellowish eyes or skin, then seek your doctor attention immediately. Stay away from too much exposure to sunlight or tanning beds because Depakote Generic can allow you burn the more with ease. Put on sun-block and protective dresses anytime you are outdoors. In order to monitor the effects of this medication, blood tests may be required.

Dosage The tablets are designed for oral use and are supplied in three dosage strengths in which each of the dose strength contains Divalproex Sodium that is almost the same as 125mg, 250mg or 500 mg of Valproic acid. Seizures IQ: When the concentration of the blood is 50-100mcg per ml, then that is the expected result. It shows that it is responsive. Acute Mania: If you are experience acute mania because of the bipolar disorder, the treatment begins with 750mg in a day of delayed-release tablets but the dose must be divided.

Later, the dosage can be increased rapidly so as to attain the expected result. The recommended dose of Divalproex is 250mg two times daily. The highest recommended dosage is 1000mg per day. If you are using extended release tablets, then the 500-1000 mg dosage once in a day is highly appreciated. Side Effects Due to the fact that one of the risks of Depakote Generic Divalproex is an increase in the chance of damaging the liver, it is necessary to monitor the following symptoms: Jaundice; Swollen face, arms, hands, legs, and feet; Dark urination; Stomach pain at the right side; Loss of appetite; Consistent vomiting; Nausea. Depakote has a high tendency to make a person suffering from suicidal thoughts.

Immediately consult your doctor if you have any of the symptoms listed below:

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To be sure Generic Depakote is not causing harmful effects, your liver function will need to be tested. Visit your doctor regularly. Do not stop using Generic Depakote without first talking to your doctor, even if you feel fine. Seek emergency medical attention if the person taking Generic Depakote has nausea, vomiting, upper stomach pain, or loss of appetite, low fever, dark urine, clay-colored stools, or jaundice yellowing of the skin or eyes. These symptoms may be early signs of liver damage or pancreatitis. Divalproex is also used to augment the effect of antidepressants during the treatment of serious anxiety and depression. Currently, the treatment mechanism of Depakote is unknown, but is believed to be associated with an increase in the concentration of GABA gamma-aminobutyric acid found in the brain.

Gamma-aminobutyric acid is recognized as a repressive neurotransmitter that slows the rate of firing in the brain and muscle cells. Divalproex is not an addictive drug. Important to Know Depakote should not be recommended to patients suffering from hepatic disease or certain hepatic dysfunction, as well as from disorders of the urea cycle. The Depakote Generic Divalproex medication is consulted in patients suffering from mitochondrial disorders that result from mutations in the mitochondrial DNA polymerase. It is also contraindicated for children under 2 years of age who are not trusted with disorders related to POLG.

Depakote is recommended for use in pregnant women suffering from migraine headaches. Instructions on Taking Divalproex can be used to treat mania, epilepsy, as well as to prevent migraine occurrence. The medication can be taken either as a single drug or in combination with other anti-epileptic drugs. In small forms of epilepsy, valproic acid is usually administered alone. The medication is taken orally after a meal or during a meal. The treatment is started with small doses with a gradual increase within one to two weeks until the desired therapeutic effect is achieved. Then, the optimal maintenance dose is selected. The daily dosage for adults at the beginning of the treatment is one or two pills 300 mg pills.

Then it is gradually increased to 900 mg-1500 mg. The single intake dose is 300-450 mg. The maximum daily dose is 2400 mg. For the therapy of migraines, it is desirable to stick to the low doses. For the treatment of children, the dosages are selected individually based on the age, the severity of the condition, and therapeutic effect. Usually, the daily dose for children is from 20 to 50 mg per kilogram of the body weight. The maximum is 60 mg per kilogram. The treatment is started with 15 mg per kilogram then the dose is raised by 5-10 mg till the desired effect is achieved. The following products are equivalent to Depakote: January 23, 2009 Strength s: March 28, 2011 Strength s: January 27, 2009 Strength s: February 25, 2011 Strength s: November 3, 2008 Strength s:

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